产品货号：
Z34395
中文名称：
MFN2抗体
英文名称：
Anti-MFN2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MFN2 Antibody |
| 指标别名 | CMT2A;CMT2A2;CPRP1;HSG;KIAA0214;MARF;MFN2;Mitofusin 2;Transmembrane GTPase MFN2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | MFN2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Mitofusin 2 |
| 实际分子量 | 86KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Mitofusin 2(MFN2) is a mitochondrial transmembrane GTPase regulating mitochondrial fusion and that the nucleotide-dependent activation of MFN2 concomitantly protects the organelle from permeability transition.It is mapped to chromosome 1 and encodes a 757-amino acid protein that contains an ATP/GTP-binding site motif.It is expressed in many tissues and cell lines such as brain and KG-1 with the highest expression in heart and skeletal muscle.This protein contains an N-terminal GTPase domain and a transmembrane domain near the C terminus.It shares 60% identity with MFN1.When stably expressed in COS-7 cells,MFN2 colocalizes with mitochondrial markers.Axonal CMT type 2A and autosomal dominant HMSN VI are caused by MFN2 and mutations in MFN2,which emphasizes its important role of mitochondrial function for both optic atrophies and peripheral neuropathies. |
| Uniprot ID | O95140 |
| 基因名全称 | Mitofusin-2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
相关搜索：MFN2抗体，MFN2单抗，Anti-MFN2 Antibody