
产品货号:
Z34257
中文名称:
TERT抗体
英文名称:
Anti-TERT Antibody (Clone#17T17)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TERT Antibody (Clone#17T17) |
指标别名 | TCS1;HEST2;EST2;TRT;Telomerase reverse transcriptase;Telomerase-associated protein 2;Telomerase catalytic subunit |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,FCM |
基因名称 | TERT |
克隆号 | 17T17 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human TERT |
实际分子量 | 127KD |
成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | TERT(Telomerase reverse transcriptase),is a catalytic subunit of the enzyme telomerase.Its absence(usually as a result of a chromosomal mutation) is associated with the disorder Cri du chat.The TERT gene was mapped to chromosome 5p15.33T by Meyerson,M.Elomerase lengthens telomeres in DNA strands,thereby allowing senescent cells that would otherwise become postmitotic and undergo apoptosis to exceed the Hayflick limit and become potentially immortal,as is often the case with cancerous cells.Telomerase expression plays a role in cellular senescence,as it is normally repressed in postnatal somatic cells,resulting in progressive shortening of telomeres.Deregulation of telomerase expression in somatic cells may be involved in oncogenesis.Studies in mice suggest that telomerase also participates in chromosomal repair,since de novo synthesis of telomere repeats may occur at double-stranded breaks. |
Uniprot ID | O14746 |
基因名全称 | Telomerase reverse transcriptase|EC 2.7.7.49|HEST2|Telomerase catalytic subunit|Telomerase-associated protein 2|TP2 |
推荐稀释比 | Western blot (WB) 1:500~1000 IHC 1:50~100 |
相关搜索:TERT抗体,TERT单抗,Anti-TERT Antibody (Clone#17T17)