产品货号：
Z34014
中文名称：
S100 Beta/S100B抗体
英文名称：
Anti-S100 Beta/S100B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-S100 Beta/S100B Antibody |
| 指标别名 | NEF;Protein S100 B;S 100 protein beta chain;S 100 protein subunit beta;S100;S100 Beta;S100 calcium binding protein B;S100B;S100beta |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat,goat |
| 应用范围 | WB,IHC,ICC/IF,IP |
| 基因名称 | S100B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human S100B |
| 实际分子量 | 11KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | S100 calcium binding protein B or S100B is a protein of the S-100 protein family.S100 genes include at least 13 members which are located as a cluster on chromosome 1q21;however,this gene is located at 21q22.3.S100B is a glial-derived protein that is a well-established biomarker for severity of neurological injury and prognosis for recovery.S100 beta is a calcium-binding protein that is expressed at high levels in brain primarily by astrocytes.Addition of the disulfide-bonded dimeric form of S100 beta to primary neuronal and glial cultures and established cell lines induces axonal extension and alterations in astrocyte proliferation and phenotype,but evidence that S100 beta exerts the same effects in vivo has not been presented.Reeves et al.(1994) demonstrated that the same effects of the S100B protein are exerted in vivo.They found that both astrocytosis and neurite proliferation occurred in transgenic mice expressing elevated levels of S100b.They suggested that these transgenic mice represent a useful model for studies of the role of S100B in glial-neuronal interactions in normal development and function of the brain and for analyzing the significance of elevated levels of the protein in Down syndrome and Alzheimer disease. |
| Uniprot ID | P04271 |
| 基因名全称 | Protein S100-B |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 |
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