产品货号：
Z33912
中文名称：
SIRT1抗体
英文名称：
Anti-SIRT1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIRT1 Antibody |
| 指标别名 | hSIR2;hSIRT1;SIR2 like protein 1;SIR2L1;SIRT1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | SIRT1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human SIRT1 This gene encodes a member of the sirtuin family of proteins,homologs to the yeast Sir2 protein.Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.The functions of human sirtuins have not yet been determined;however,yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. |
| 实际分子量 | 110～120KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Sirtuin 1,also known as SIR2L1 or SIRT1,is a protein that in humans is encoded by the SIRT1 gene.It is mapped to 10q21.3.Sirtuin 1 is a member of the sirtuin family of proteins,homologs of the Sir2 gene in S.cerevisiae.Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.Sirtuin 1 is downregulated in cells that have high insulin resistance and inducing its expression increases insulin sensitivity,suggesting the molecule is associated with improving insulin sensitivity.Furthermore,Sirtuin 1 was shown to de-acetylate and affect the activity of both members of the PGC1-alpha/ERR-alpha complex,which are essential metabolic regulatory transcription factors. |
| Uniprot ID | Q96EB6 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
相关搜索：SIRT1抗体，SIRT1单抗，Anti-SIRT1 Antibody