
产品货号:
Z33830
中文名称:
SMAD1 (Ab-465)抗体
英文名称:
Anti-SMAD1 (Ab-465) Antibody (Clone#OTI2D2)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SMAD1 (Ab-465) Antibody (Clone#OTI2D2) |
指标别名 | BSP 1;BSP1;hSMAD1;JV4 1;JV41;MAD homolog 1;Mad related protein 1;MADH1;MADR1;Mothers against DPP homolog 1;SMAD 1;SMAD family member 1;SMAD1 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | SMAD1 |
克隆号 | OTI2D2 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human SMAD1(NP_001003688) produced in HEK293T cell. |
实际分子量 | 52.1KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | The protein encoded by this gene belongs to the SMAD,a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C.elegans gene Sma.SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.This protein mediates the signals of the bone morphogenetic proteins (BMPs),which are involved in a range of biological activities including cell growth,apoptosis,morphogenesis,development and immune responses.In response to BMP ligands,this protein can be phosphorylated and activated by the BMP receptor kinase.The phosphorylated form of this protein forms a complex with SMAD4,which is important for its function in the transcription regulation.This protein is a target for SMAD-specific E3 ubiquitin ligases,such as SMURF1 and SMURF2,and undergoes ubiquitination and proteasome-mediated degradation.Alternatively spliced transcript variants encoding the same protein have been observed.[provided by RefSeq,Jul 2008] |
Uniprot ID | Q15797 |
基因名全称 | SMAD family member 1/2/3/5 |
蛋白名全称 | Mothers against decapentaplegic homolog 1/2/3/5 |
推荐稀释比 | Western blot (WB) 1:4000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索:SMAD1 (Ab-465)抗体,SMAD1 (Ab-465)单抗,Anti-SMAD1 (Ab-465) Antibody (Clone#OTI2D2)