产品货号:
Z33814
中文名称:
SMAD4抗体
英文名称:
Anti-SMAD4 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SMAD4 Antibody |
指标别名 | DPC4;hSMAD4;JIP;MAD homolog 4;MADH4;Mothers against DPP homolog 4;SMAD 4;SMAD family member 4;SMAD4 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | SMAD4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Smad4 |
实际分子量 | 60KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | SMAD4 (Mothers Against Decapentaplegic Drosophila Homolog of 4),also known as MADH4 or DPC4,is a protein that in humans is encoded by the SMAD4 gene.It belongs to the Darfwin family of proteins that modulate members of the TGFβ protein superfamily.Hahn et al.(1996) identified the SMAD4 gene on chromosome 18q21.1.Howe et al.(1998) identified the SMAD4 gene within a region on 18q21.1 defined by linkage analysis in kindred with juvenile polyposis syndrome.To test directly the hypothesis that the SMAD4 gene is a tumor suppressor that is critical for transmitting signals from transforming growth factor-beta and related ligands.SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by mediating transcriptional activation of target genes. |
Uniprot ID | Q13485 |
基因名全称 | Mothers against decapentaplegic homolog 4 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 |
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