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所在位置:所有产品 > 抗体抗原 > 一抗 > RPA2抗体
RPA2抗体图片
产品货号:
Z33747
中文名称:
RPA2抗体
英文名称:
Anti-RPA2 Antibody (Clone#OTI10G1)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-RPA2 Antibody (Clone#OTI10G1)
指标别名REPA2;Replication factor A protein 2;replication protein A2;32kDa;RF A protein 2;RP A p32;RP A p34;RPA2;RPA32;RPA34
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,IHC,FCM
基因名称RPA2
克隆号OTI10G1
抗体来源Mouse
抗体类型IgG1
免疫原Full length human recombinant protein of human RPA2 (NP_002937) produced in HEK293T cell.
实际分子量29.1KD
成分PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide.
纯化方式Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度500μg/mL
产品形态溶液
保存条件Stable for 12 months from date of receipt.Store at -20℃ as received.
背景资料This gene encodes a subunit of the heterotrimeric Replication Protein A (RPA) complex,which binds to single-stranded DNA (ssDNA),forming a nucleoprotein complex that plays an important role in DNA metabolism,being involved in DNA replication,repair,recombination,telomere maintenance,and co-ordinating the cellular response to DNA damage through activation of the ataxia telangiectasia and Rad3-related protein (ATR) kinase.The RPA complex protects single-stranded DNA from nucleases,prevents formation of secondary structures that would interfere with repair,and co-ordinates the recruitment and departure of different genome maintenance factors.The heterotrimeric complex has two different modes of ssDNA binding,a low-affinity and high-affinity mode,determined by which oligonucleotide/oligosaccharide-binding (OB) domains of the complex are utilized,and differing in the length of DNA bound.This subunit contains a single OB domain that participates in high-affinity DNA binding and also contains a winged helix domain at its carboxy terminus,which interacts with many genome maintenance protein.Post-translational modifications of the RPA complex also plays a role in co-ordinating different damage response pathways.
Uniprot IDP15927
基因名全称Replication protein A 32kDa subunit
推荐稀释比
Western blot (WB) 1:4000
Immunohistochemistry in paraffin section (IHC) 1:50
Flow cytometry (FCM) 1:100

相关搜索:RPA2抗体RPA2单抗Anti-RPA2 Antibody (Clone#OTI10G1)
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