产品货号：
Z33639
中文名称：
STAT1 Purified抗体
英文名称：
Anti-STAT1 Purified Antibody (Clone#SM1)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-STAT1 Purified Antibody (Clone#SM1) |
| 指标别名 | ISGF 3;STAT1;STAT91 |
| 克隆性 | Monoclonal |
| 检验物种 | mouse,human |
| 应用范围 | IP,WB,IHC |
| 基因名称 | STAT1 |
| 克隆号 | SM1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | STAT1 peptide sequence 721-733 (DNLLPMSPEEFDE).The antibody SM1 recognizes an epitope included within amino acids 721-733 of STAT1,a 91kDa transcriptional factor involved in a variety of systems including antiviral responses and interferon alpha (IFN-alpha) and gamma (IFN-gamma) signal transduction. |
| 计算分子量 | 87kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | STAT1 (signal transducer and activator of transcription 1) is a transcription factor that plays important roles in growth arrest,apoptosis promoting and tumour suppression.After ligation of cytokine receptors STAT1 becomes phosphorylated on Tyr701 by Janus kinase JAK1 or JAK2,dimerizes,translocates to nucleus and contacts DNA.STAT1-STAT2 heterodimers serve as more potent transcriptional inducers than STAT1 homodimers.STAT1 is also phosphorylated on Ser727 by MAPK pathway,independently of tyrosine phosphorylation.However,the both modifications are important for its maximal transcriptional activity.On the other hand,STAT1 phosphorylated on Ser727 is targeted for proteasomal degradation. |
| Uniprot ID | P42224 |
| 基因名全称 | Signal transducer and activator of transcription 1 |
| 蛋白名全称 | Signal transducer and activator of transcription 1-alpha/beta |
| 推荐稀释比 | Immunohistochemistry (paraffin sections):5μg/mL;positive tissue:lung macrophages. Western blotting:1～2μg/mL. |
相关搜索：STAT1 Purified抗体，STAT1 Purified单抗，Anti-STAT1 Purified Antibody (Clone#SM1)