产品货号：
Z33601
中文名称：
BubR1/BUB1B抗体
英文名称：
Anti-BubR1/BUB1B Antibody (Clone#8B3)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BubR1/BUB1B Antibody (Clone#8B3) |
| 指标别名 | Bub1A;BUB1B;BUB1beta;BubR1;hBUBR1;MAD3L;Protein SSK1;SSK1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | BUB1B |
| 克隆号 | 8B3 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human BubR1/BUB1B recombinant protein (Position:K26-E448). |
| 实际分子量 | 130KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene.This gene encodes a kinase involved in spindle checkpoint function.The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C),delaying the onset of anaphase and ensuring proper chromosome segregation.Impaired spindle checkpoint function has been found in many forms of cancer. |
| Uniprot ID | O60566 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | BUB1 mitotic checkpoint serine/threonine kinase B |
| 蛋白名全称 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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