产品货号：
Z33480
中文名称：
BBS4抗体(Center)
英文名称：
Anti-BBS4 Antibody(Center)(Clone#1292CT845.130.218)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BBS4 Antibody (Center) (Clone#1292CT845.130.218) |
| 指标别名 | Bardet Biedl syndrome 4;BBS4 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | BBS4 |
| 克隆号 | 1292CT845.130.218 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | This BBS4 antibody is generated from a mice immunized with a recombinant protein between 1-240 amino acids from human BBS4. |
| 计算分子量 | 58kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia.The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor,which localizes to the basal body and contacts the BBSome.Rab8 (GTP) enters the primary cilium and promotes extension of the ciliary membrane.Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8,the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.The BBSome complex,together with the LTZL1,controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation.Required for proper BBSome complex assembly and its ciliary localization.Required for microtubule anchoring at the centrosome but not for microtubule nucleation.May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome. |
| Uniprot ID | Q96RK4 |
相关搜索：BBS4抗体(Center)，BBS4单抗