产品货号：
Z33477
中文名称：
BAK/BAK1抗体
英文名称：
Anti-BAK/BAK1 Antibody (Clone#4C2)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BAK/BAK1 Antibody (Clone#4C2) |
| 指标别名 | Apoptosis regulator BAK;BAK;BAK LIKE;BAK1;CDN1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | BAK1 |
| 克隆号 | 4C2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human BAK/BAK1 recombinant protein (Position:A22-S211).Human BAK shares 78.3% amino acid (aa) sequence identity with mouse BAK. |
| 实际分子量 | 23～25KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BAK,officially called Bcl2 antagonist killer,is a protein that in humans,encoded by the BAK gene.The BAK protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis.BAK gene spans 7.6kb and contains 6 exons.By Southern blot analysis of genomic DNA from human/rodent somatic cell hybrids,BAK gene is localized to chromosome 6.This protein localizes to mitochondria,and functions to induce apoptosis.It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel,which leads to a loss in membrane potential and the release of cytochrome.This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
| Uniprot ID | Q16611 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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