产品货号：
Z33404
中文名称：
ATP2A1抗体
英文名称：
Anti-ATP2A1 Antibody (Clone#24A90)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATP2A1 Antibody (Clone#24A90) |
| 指标别名 | ATP2A;ATP2A1;Calcium pump 1;SERCA1;SR Ca(2+) ATPase 1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | ATP2A1 |
| 克隆号 | 24A90 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human SERCA1 ATPase |
| 实际分子量 | 110KD |
| 成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SERCA1(SARCOPLASMIC RETICULUM Ca(2+)-ATPase 1),also called ATP2A1,is an enzyme that in humans is encoded by the ATP2A1 gene.This gene encodes one of the SERCA Ca(2+)-ATPases,which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells.The SERCA1 gene is mapped on 16p11.2.This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen,and is involved in muscular excitation and contraction.Zhang et al.(1995)determined that the human ATP2A1 gene is 26kb long and contains 23 exons,1 of which can be alternatively spliced.Overexpression of S1T,but not full-length SERCA1,induced ER stress in HeLa cells and amplified ER stress through the PERK(EIF2AK3)-EIF2A -ATF4 -CHOP(DDIT3) pathway.Mutations in this gene cause some autosomal recessive forms of Brody disease,characterized by increasing impairment of muscular relaxation during exercise. |
| Uniprot ID | O14983 |
| 基因名全称 | ATPase,Ca++ transporting,cardiac muscle,fast twitch 1 |
| 蛋白名全称 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(SERCA1/SR Ca(2+)-ATPase 1) |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：ATP2A1抗体，ATP2A1单抗，Anti-ATP2A1 Antibody (Clone#24A90)