产品货号：
Z33368
中文名称：
Bcl-XL/BCL2L1抗体
英文名称：
Anti-Bcl-XL/BCL2L1 Antibody (Clone#OTI4A9)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Bcl-XL/BCL2L1 Antibody (Clone#OTI4A9) |
| 指标别名 | Apoptosis regulator Bcl X;BCL2L1;Bcl-XL |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IF |
| 基因名称 | BCL2L1 |
| 克隆号 | OTI4A9 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Recombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL |
| 实际分子量 | 25.9KD |
| 成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 0.25mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Bcl-2-like protein 1,also known as Bcl-XL,is a protein that in humans is encoded by the BCL2L1 gene.The protein encoded by this gene belongs to the BCL-2 protein family.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The proteins encoded by this gene are located at the outer mitochondrial membrane,and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening.VDAC regulates mitochondrial membrane potential,and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria,both of which are the potent inducers of cell apoptosis.Alternative splicing results in multiple transcript variants encoding two different isoforms.The longer isoform (Bcl-xL) acts as an apoptotic inhibitor and the shorter form (Bcl-xS) acts as an apoptotic activator. |
| Uniprot ID | Q07817 |
| 基因名全称 | BCL2-like 1 |
| 蛋白名全称 | Bcl-2-like protein 1(Bcl2-L-1) |
| 推荐稀释比 | Western blot (WB) 1:200～1000 Immunofluorescence (IF) 1:100 |
相关搜索：Bcl-XL/BCL2L1抗体，Bcl-XL抗体，BCL2L1单抗，Anti-Bcl-XL/BCL2L1 Antibody (Clone#OTI4A9)