产品货号：
Z33336
中文名称：
BAG2抗体
英文名称：
Anti-BAG2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BAG2 Antibody |
| 指标别名 | BAG 2;BAG2;dJ417I1.2;KIAA0576 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | BAG2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human BAG2 Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. |
| 实际分子量 | 24KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene.The predicted BAG2 protein contains 211 amino acids.The BAG domains of BAG1,BAG2,and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells.All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins,with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation. |
| Uniprot ID | O95816 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：BAG2抗体，BAG2单抗，Anti-BAG2 Antibody