产品货号：
Z33335
中文名称：
BAG3抗体
英文名称：
Anti-BAG3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BAG3 Antibody |
| 指标别名 | BAG 3;BAG3;BIS;CAIR 1;Docking protein CAIR 1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IP |
| 基因名称 | BAG3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Bag3 Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.Has anti-apoptotic activity. |
| 实际分子量 | 80KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BAG family molecular chaperone regulator 3(BAG3) is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones.BAG3 mutations are responsible for familial dilated cardiomyopathy.BAG3 polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus.In muscle cells,BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes.This process is called chaperone-assisted selective autophagy (CASA) and is essential for maintaining muscle activity in flies,mice and men. |
| Uniprot ID | O95817 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100Immunocoprecipitation 1:20 |
相关搜索：BAG3抗体，BAG3单抗，Anti-BAG3 Antibody