产品货号：
Z33315
中文名称：
BTK抗体
英文名称：
Anti-BTK Antibody (Clone#7F12H4)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BTK Antibody (Clone#7F12H4) |
| 指标别名 | AGMX1;AT;ATK;B cell progenitor kinase;BPK;Bruton tyrosine kinase;BTK;IMD1;PSCTK1;Tyrosine protein kinase BTK;XLA |
| 克隆性 | Monoclonal |
| 检验物种 | human,monkey |
| 应用范围 | WB,IHC,IF,ELISA |
| 基因名称 | BTK |
| 克隆号 | 7F12H4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Purified recombinant fragment of Btk expressed in E.Coli. |
| 计算分子量 | 76KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | BTK,also known as Bruton's tyrosine kinase,is an enzyme that in humans is encoded by the BTK gene.It is mapped to Xq22.1.BTK plays a crucial role in B cell maturation as well as mast cell activation through the high-affinity IgE receptor.BTK contains a PH domain that binds phosphatidylinositol (3,4,5)-trisphosphate (PIP3).PIP3 binding induces BTK to phosphorylate phospholipase C,which in turn hydrolyzes PIP2,a phosphatidylinositol,into two second messengers,inositol triphosphate (IP3) and diacylglycerol (DAG),which then go on to modulate the activity of downstream proteins during B-cell signalling.This gene also regulates both TLR9 activation and expression in B lymphocytes and is necessary for inhibitory cytokine expression. |
| Uniprot ID | Q06187 |
| 基因名全称 | Tyrosine-protein kinase BTK |
| 蛋白名全称 | Tyrosine-protein kinase BTK |
| 推荐稀释比 | WB 1:500～1:2000 IHC 1:200～1:1000 IF 1:200～1:1000 ELISA 1:10000 |
相关搜索：BTK抗体，BTK单抗，Anti-BTK Antibody (Clone#7F12H4)