产品货号：
Z33219
中文名称：
Calcium Sensing Receptor/CASR抗体
英文名称：
Anti-Calcium Sensing Receptor/CASR Antibody (Clone#11E9)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Calcium Sensing Receptor/CASR Antibody (Clone#11E9) |
| 指标别名 | Calcium Sensing Receptor;CAR;CASR;FHH;FIH;GPRC2A;HHC;HHC1;NSHPT;PCAR1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,ICC,FCM |
| 基因名称 | CASR |
| 克隆号 | 11E9 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human CASR recombinant protein (Position:Q926-S1078).Human CASR shares 80.5% and 78.6% amino acid (aa) sequence identity with mouse and rat CASR,respectively. |
| 实际分子量 | 130KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland,and the cells lining the kidney tubule.It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling,thus this protein plays an essential role in maintaining mineral ion homeostasis.Mutations in this gene cause familial hypocalciuric hypercalcemia,familial,isolated hypoparathyroidism,and neonatal severe primary hyperparathyroidism. |
| Uniprot ID | P41180 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section 1:50～400 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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