产品货号：
Z33195
中文名称：
B7-1/CD80抗体
英文名称：
Anti-B7-1/CD80 Antibody (Clone#8G12)
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-B7-1/CD80 Antibody (Clone#8G12) |
| 指标别名 | Activation B7 1 antigen;B7;B7 1;B7-1;BB1;CD28LG;CD28LG1;CD80;CD80 molecule;CTLA 4 counter receptor B7.1;LAB7 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC,ICC,IF,FCM |
| 基因名称 | CD80 |
| 克隆号 | 8G12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | CD80 antibody was raised against the extracellular domain of human CD80. |
| 计算分子量 | 33kDa |
| 成分 | CD80 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol. |
| 纯化方式 | CD80 Antibody is supplied as protein A purified IgG2b. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | CD80,also known as B7-1,is a type I membrane protein that is a member of the immunoglobulin superfamily.Like the related protein CD86,this protein is expressed by antigen-presenting cells,and is the ligand for two proteins at the cell surface of T cells,CD28 and the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4).Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production.CTLA-4 binding negatively regulates T-cell activation and diminishes the immune response (1).Blocking the CTLA-4-CD80/CD86 interaction has been shown to enhance T-cell functions in acute lymphoblastomic leukemia (ALL),suggesting that this pathway may be an attractive target for future cancer immunotherapy (2). |
| Uniprot ID | P33681 |
| 基因名全称 | CD80 molecule |
| 蛋白名全称 | CD80 molecule |
| 推荐稀释比 | CD80 antibody can be used for immunohistochemistry starting at 2 ～ 5μg/mL.For immunofluorescence start at 5μg/mL.Flow cytometry at 10μg/mL.Antibody validated:Immunohistochemistry in human samples;Immunocytochemistry in human samples;Immunofluorescence in human samples and Flow Cytometry in mouse samples.All other applications and species not yet tested. |
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