产品货号：
Z33078
中文名称：
Annexin A1/ANXA1抗体
英文名称：
Anti-Annexin A1/ANXA1 Antibody (Clone#5E4-D8-F12)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Annexin A1/ANXA1 Antibody (Clone#5E4-D8-F12) |
| 指标别名 | Annexin 1;annexin A1;Annexin I;ANX1;ANXA1;Calpactin 2;Calpactin II;Chromobindin 9;Lipocortin I;LPC1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat,monkey |
| 应用范围 | WB,ELISA |
| 基因名称 | ANXA1 |
| 克隆号 | 5E4-D8-F12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Purified recombinant human Annexin A1 beta protein fragments expressed in E.coli. |
| 计算分子量 | 39KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | ANXA1,also known as lipocortin I or Annexin A1,is a protein that in humans is encoded by the ANXA1 gene.It is mapped to 9q21.13.ANXA1 belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane.ANXA1 protein has an apparent relative molecular mass of 40kDa,with phospholipase A2 inhibitory activity.Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway.This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge.These findings identified ANXA1 peptides as novel,endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects. |
| Uniprot ID | P04083 |
| 基因名全称 | Annexin A1 |
| 蛋白名全称 | Annexin A1 |
| 推荐稀释比 | WB 1:500～2000 ELISA 1:10000～20000 |
相关搜索：Annexin A1/ANXA1抗体，Annexin A1抗体，ANXA1单抗，Anti-Annexin A1/ANXA1 Antibody (Clone#5E4-D8-F12)