产品货号:
Z33041
中文名称:
AKT3抗体
英文名称:
Anti-AKT3 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AKT3 Antibody |
指标别名 | AKT3;PKB GAMMA;PKBG;PRKBG;Protein kinase Akt 3;Protein kinase B gamma;RAC gamma;RAC PK gamma;STK 2 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | AKT3 |
克隆号 | 3B12F3F10/2D2B11B11/2D2B11H5 |
抗体来源 | Mouse |
免疫原 | Purified recombinant fragment of Akt3 expressed in E.Coli. |
计算分子量 | 56KD |
成分 | Ascitic fluid containing 0.03% sodium azide. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | RAC-gamma serine/threonine-protein kinase,also known as protein kinase Akt-3,is an enzyme that in humans is encoded by the AKT3 gene.This gene is mapped to 1q43-q44.The protein encoded by this gene is a member of the AKT,also called PKB,serine/threonine protein kinase family.AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors.They are involved in a wide variety of biological processes including cell proliferation,differentiation,apoptosis,tumorigenesis,as well as glycogen synthesis and glucose uptake.This kinase has been shown to be stimulated by platelet-derived growth factor(PDGF),insulin,and insulin-like growth factor 1(IGF1).AKT3 plays an important role in brain development and is crucial for the viability of malignant glioma cells.AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13.This gene is required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. |
Uniprot ID | Q9Y243 |
基因名全称 | RAC-gamma serine/threonine-protein kinase |
蛋白名全称 | RAC-gamma serine/threonine-protein kinase |
推荐稀释比 | WB 1:500~1:2000 ELISA 1:10000 |
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