产品货号：
Z32969
中文名称：
Androgen receptor/AR抗体
英文名称：
Anti-Androgen receptor/AR Antibody (Clone#OTI1D3)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Androgen receptor/AR Antibody (Clone#OTI1D3) |
| 指标别名 | AIS;androgen receptor;AR;DHTR;Dihydrotestosterone receptor;HUMARA;HYSP1;KD;NR3C4;SBMA;SMAX1;TFM |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | AR |
| 克隆号 | OTI1D3 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 420-659 of human AR(NP_000035) produced in E.coli. |
| 实际分子量 | 99KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | The androgen receptor gene is more than 90kb long and codes for a protein that has 3 major functional domains:the N-terminal domain,DNA-binding domain,and androgen-binding domain.The protein functions as a steroid-hormone activated transcription factor.Upon binding the hormone ligand,the receptor dissociates from accessory proteins,translocates into the nucleus,dimerizes,and then stimulates transcription of androgen responsive genes.This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein.Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease).Mutations in this gene are also associated with complete androgen insensitivity (CAIS).Two alternatively spliced variants encoding distinct isoforms have been described.[provided by RefSeq,Jul 2008] |
| Uniprot ID | P10275 |
| 基因名全称 | androgen receptor |
| 蛋白名全称 | Androgen receptor |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索：Androgen receptor/AR抗体，Androgen receptor抗体，AR单抗，Anti-Androgen receptor/AR Antibody (Clone#OTI1D3)