产品货号：
Z32960
中文名称：
AMPK Alpha 2/PRKAA2抗体
英文名称：
Anti-AMPK Alpha 2/PRKAA2 Antibody (Clone#206CT5.4.2)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AMPK Alpha 2/PRKAA2 Antibody (Clone#206CT5.4.2) |
| 指标别名 | AMPK;AMPK alpha 2;AMPK subunit alpha 2;AMPK2;AMPKA2;AMPKα2;PRKAA;PRKAA2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | IF,WB |
| 基因名称 | PRKAA2 |
| 克隆号 | 206CT5.4.2 |
| 抗体来源 | Mouse |
| 免疫原 | This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein. |
| 计算分子量 | 62kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK).AMPK is a heterotrimer consisting of an alpha catalytic subunit,and non-catalytic beta and gamma subunits.AMPK is an important energy-sensing enzyme that monitors cellular energy status.In response to cellular metabolic stresses,AMPK is activated,and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR),key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol.Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. |
| Uniprot ID | P54646 |
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