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产品目录

Androgen receptor/AR抗体图片
产品货号:
Z32955
中文名称:
Androgen receptor/AR抗体
英文名称:
Anti-Androgen receptor/AR Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Androgen receptor/AR Antibody
指标别名AIS;androgen receptor;AR;DHTR;Dihydrotestosterone receptor;HUMARA;HYSP1;KD;NR3C4;SBMA;SMAX1;TFM
克隆性Monoclonal
检验物种human
应用范围WB,IHC
基因名称AR
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human Androgen Receptor(AR-V7 specific)
实际分子量80KD(AR-V7specific)
成分500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
纯化方式Affinity-chromatography
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料The AR (androgen receptor) gene is more than 90kb long and codes for a protein that has 3 major functional domains:the N-terminal domain,DNA-binding domain,and androgen-binding domain.The AR gene is mapped to Xq12.The protein functions as a steroid-hormone activated transcription factor.Upon binding the hormone ligand,the receptor dissociates from accessory proteins,translocates into the nucleus,dimerizes,and then stimulates transcription of androgen responsive genes.This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein.Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease).Mutations in this gene are also associated with complete androgen insensitivity (CAIS).Two alternatively spliced variants encoding distinct isoforms have been described.
Uniprot IDC0JKD3
基因名全称Androgen receptor
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:20~100

相关搜索:Androgen receptor/AR抗体Androgen receptor抗体AR单抗Anti-Androgen receptor/AR Antibody
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