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所在位置:所有产品 > 抗体抗原 > 一抗 > AIF/AIFM1抗体
AIF/AIFM1抗体图片
产品货号:
Z32949
中文名称:
AIF/AIFM1抗体
英文名称:
Anti-AIF/AIFM1 Antibody (Clone#OTI4E6)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-AIF/AIFM1 Antibody (Clone#OTI4E6)
指标别名AIF;AIFM1;Mitochondrion Marker;PDCD8
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,IHC
基因名称AIFM1
克隆号OTI4E6
抗体来源Mouse
抗体类型IgG2a
免疫原Human recombinant protein fragment corresponding to amino acids 134-483 of human AIFM1 (NP_001124318) produced in E.coli.
成分PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide.
纯化方式Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度500μg/mL
产品形态溶液
保存条件Stable for 12 months from date of receipt.Store at -20℃ as received.
背景资料Apoptosis-inducing factor 1,mitochondrial,also known as AIF or PDCD8 is a protein that in humans is encoded by the AIFM1 gene.AIFM1 gene is mapped to Xq26.1 based on an alignment of the AIFM1 sequence with the genomic sequence.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells,and it is found in the mitochondrial intermembrane space in healthy cells.Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation.In addition,this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.Mutations in this gene cause combined oxidative phosphorylation deficiency 6,which results in a severe mitochondrial encephalomyopathy.A related pseudogene has been identified on chromosome 10.
Uniprot IDO95831
基因名全称apoptosis-inducing factor,mitochondrion-associated,1
蛋白名全称Apoptosis-inducing factor 1,mitochondrial
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:500

相关搜索:AIF/AIFM1抗体AIF抗体AIFM1单抗Anti-AIF/AIFM1 Antibody (Clone#OTI4E6)
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