AHNAK Purified抗体

产品货号：

Z32943

中文名称：

AHNAK Purified抗体

英文名称：

Anti-AHNAK Purified Antibody (Clone#EM-09)

产品规格：

0.1mg(C100)

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-AHNAK Purified Antibody (Clone#EM-09)
指标别名	AHNAK,AHNAK nucleoprotein,AHNAKRS,Desmoyokin,PM227
克隆性	Monoclonal
检验物种	human,mouse
应用范围	WB,IHC-F,ICC,IP
基因名称	AHNAK
克隆号	EM-09
抗体来源	Mouse
抗体类型	IgG1
免疫原	Bacterially expressed fragment of N-terminal domain of human AHNAK1.The mouse monoclonal antibody EM-09 reacts with AHNAK1,a 700kDa multi-functional adaptor protein expressed mainly in epithelial cell,various types of muscle cells and immune cells.
计算分子量	629kDa
成分	Phosphate buffered saline (PBS),pH7.4,15mM sodium azide
纯化方式	Purified by protein-A affinity chromatography.
浓度	1mg/mL
产品形态	溶液
保存条件	Store at 2～8℃.Do not freeze.
背景资料	AHNAK1 (Desmoyokin) is a large (700kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca²⁺ channels.AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation.In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane,connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture.In epithelial cells,AHNAK1 is localized in cytoplasm or is membrane-associated,but in cells of nonepithelial origin AHNAK1 is predominantly nuclear;it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.
Uniprot ID	Q09666
基因名全称	AHNAK1 nucleoprotein
蛋白名全称	Neuroblast differentiation-associated protein AHNAK
推荐稀释比	Immunocytochemistry:Positive control:HeLa human cervix carcinoma cell line,permeabilization is required. Western blotting:Positive control:HeLa human cervix carcinoma cell line.

产品目录