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产品目录

CD146/MCAM抗体图片
产品货号:
Z32903
中文名称:
CD146/MCAM抗体
英文名称:
Anti-CD146/MCAM Antibody (Clone#4C12)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-CD146/MCAM Antibody (Clone#4C12)
指标别名CD146;MCAM;MUC18
克隆性Monoclonal
检验物种human
应用范围WB,IHC,IHC-F,FCM
基因名称MCAM
克隆号4C12
抗体来源Mouse
抗体类型IgG2a
免疫原E.coli-derived human CD146 recombinant protein (Position:H59-A401).Human CD146 shares 73% amino acid (aa) sequence identity with both mouse and rat CD146.
实际分子量100KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式protein G purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料CD146 (cluster of differentiation 146),also known as the melanoma cell adhesion molecule (MCAM) or cell surface glycoprotein MUC18,is a 113kDa cell adhesion molecule currently used as a marker for endothelial cell lineage.MCAM,a member of the immunoglobulin superfamily,is homologous to several cell adhesion molecules and is associated with tumor progression and the development of metastasis in human malignant melanoma.By radiation hybrid analysis,this gene is mapped to chromosome 11q23.3.MCAM has been demonstrated to appear on a small subset of T and B lymphocytes in the peripheral blood of healthy individuals.MCAM has been seen as a marker for mesenchymal stem cells isolated from multiple adult and fetal organs,and its expression may be linked to multipotency mesenchymal stem cells with greater differentiation potential express higher levels of MCAM on the cell surface.
Uniprot IDP43121
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC.
基因名全称melanoma cell adhesion molecule
蛋白名全称Cell surface glycoprotein MUC18
推荐稀释比
Flow cytometry (FCM) 1~3μg/1×106 cells
Western blot(WB) 1:500~2000
mmunohistochemistry in paraffin section (IHC) 1:50~400
Immunohistochemistry in frozen section (IHC-F) 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 29 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:CD146/MCAM抗体CD146抗体MCAM单抗Anti-CD146/MCAM Antibody (Clone#4C12)
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