产品货号:
Z32855
中文名称:
CSK Purified抗体
英文名称:
Anti-CSK Purified Antibody (Clone#CSK-04)
产品规格:
0.1ml(R100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CSK Purified Antibody (Clone#CSK-04) |
指标别名 | C Src kinase;c src tyrosine kinase;CSK;Protein tyrosine kinase CYL;Tyrosine protein kinase CSK |
克隆性 | Monoclonal |
检验物种 | human,mouse |
应用范围 | WB,IP,ICC |
基因名称 | CSK |
克隆号 | CSK-04 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Bacterially expressed recombinant fragment of human Csk corresponding to aa 330-450.The mouse monoclonal antibody CSK-04 reacts with Csk (C-terminal Src kinase),a 50kDa intracellular non-receptor protein tyrosine kinase. |
计算分子量 | 51kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | C-terminal Src kinase (Csk) is a non-receptor protein tyrosine kinase which resembles Src-family kinases,but unlike them it lacks the conserved autophosphorylation site,the regulatory C-terminal tyrosine as well as myristylation and palmitylation.Csk negatively regulates Src-family kinases by phosphorylation of their C-terminal regulatory tyrosine.Disruption of the csk gene causes constitutive activation of Src-family kinases,and overexpression of Csk usually counteracts their signaling.The Csk-mediated regulation of those Src-family kinases,that are localized in lipid rafts,is enabled by a ubiquitously expressed transmembrane adaptor PAG (also known as Cbp,Csk-binding protein),which recruits Csk. |
Uniprot ID | P41240 |
基因名全称 | C-terminal Src kinase |
蛋白名全称 | Tyrosine-protein kinase CSK |
推荐稀释比 | Immunocytochemistry:Positive control:HeLa human cervix carcinoma cell line. Western blotting:The recommended dilution of the antibody CSK-04 is 1:250~1:300;weak non-specific band of cca 60kDa is detected in human cell lines in lower antibody dilutions. Immunoprecipitation:The immunosorbent (CSK-04 antibody covalently bound to beads) immunoprecipitates Csk from cell lysates. |
相关搜索:CSK Purified抗体,CSK Purified单抗,Anti-CSK Purified Antibody (Clone#CSK-04)