产品货号：
Z32820
中文名称：
CHM抗体
英文名称：
Anti-CHM Antibody (Clone#27C71)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CHM Antibody (Clone#27C71) |
| 指标别名 | CHM;Choroideraemia protein;GGTA;REP1;TCD |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF |
| 基因名称 | CHM |
| 克隆号 | 27C71 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human CHM |
| 实际分子量 | 95KD |
| 成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Rab escort protein 1 (REP1) also known as rab proteins geranylgeranyltransferase component A 1 is an enzyme that in humans is encoded by the CHM gene.It is mapped to Xq21.2.This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme.In the dimeric holoenzyme,this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction.Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane.Mutations in this gene are a cause of choroideremia;also known as tapetochoroidal dystrophy (TCD).This X-linked disease is characterized by progressive dystrophy of the choroid,retinal pigment epithelium and retina.Alternatively spliced transcript variants have been found for this gene. |
| Uniprot ID | P24386 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 ICC/IF 1:50～1:200 |
相关搜索：CHM抗体，CHM单抗，Anti-CHM Antibody (Clone#27C71)