产品货号：
Z32801
中文名称：
ATG4A抗体
英文名称：
Anti-ATG4A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATG4A Antibody |
| 指标别名 | APG4A;ATG4A;AUTL2;Autophagin 2;Cysteine protease ATG4A;hAPG4A |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IP |
| 基因名称 | ATG4A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Atg4A The cysteine protease Atg4 is pivotal to autophagosome membrane generation and regulation.Atg4 primes the Atg8 homologue for lipidation by cleaving its carboxy terminus and exposing its glycine residue for E1-like enzyme Atg7.The Atg8 homologue is transferred to the E2-like enzyme Atg3 before forming the Atg8-PE conjugate.During later stages of autophagy,Atg4 can reverse this lipidation event by cleaving PE,thereby recycling the Atg8 homologue. |
| 实际分子量 | 45KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cysteine protease ATG4A is an enzyme that in humans is encoded by the ATG4A gene.It is mapped to Xq22.3.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation,metamorphosis,non-apoptotic cell death,and aging.Reduced levels of autophagy have been described in some malignant tumors,and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.This gene encodes a member of the autophagin protein family.The encoded protein is also designated as a member of the C-54 family of cysteine proteases. |
| Uniprot ID | Q8WYN0 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocoprecipitation 1:20 |
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