产品货号：
Z32429
中文名称：
CD169/SIGLEC1抗体
英文名称：
Anti-CD169/SIGLEC1 Antibody (Clone#7-239)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD169/SIGLEC1 Antibody (Clone#7-239) |
| 指标别名 | CD169;Sialoadhesin;SIGLEC 1;SIGLEC1;SN |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,WB,IHC-F |
| 基因名称 | SIGLEC1 |
| 克隆号 | 7-239 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human rhinovirus 14-infected monocyte-derived dendritic cells.The mouse monoclonal antibody 7-239 recognizes an extracellular epitope of CD169 (sialoadhesin,Siglec-1),a 210kDa type I transmembrane glycoprotein expressed on macrophages and dendritic cells. |
| 计算分子量 | 183kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD169,also known as Siglec-1 or sialoadhesin,is a type I transmembrane glycoprotein of the sialic acid binding Ig-like lectin family.It binds to sialylated glycoproteins on various haematopoietic cells to mediate cell-cell interactions.CD169 is expressed on a subset of macrophages and dendritic cells.On CD14+ monocytes its expression can be induced by interferon alpha and gamma.High expression of CD169 is observed in the spleen,lymph nodes,bone marrow,and under inflammatory conditions rheumatoid arthritis and atherosclerosis,lower in the liver,lungs and gut.It has been shown to be involved in antigen presentation to invariant NKT cells,which play an important role in the innate arm of the immune system to modulate the subsequent acquired immune responses. |
| Uniprot ID | Q9BZZ2 |
| 基因名全称 | Sialic acid binding Ig like lectin 1 |
| 蛋白名全称 | Sialoadhesin |
| 推荐稀释比 | Flow cytometry:1～4μg/mL |
相关搜索：CD169/SIGLEC1抗体，CD169抗体，SIGLEC1单抗，Anti-CD169/SIGLEC1 Antibody (Clone#7-239)