产品货号:
Z32397
中文名称:
CRX抗体
英文名称:
Anti-CRX Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CRX Antibody |
指标别名 | cone rod homeobox;Cone rod homeobox protein;CORD2;CRD;CRX;diencephalon/mesencephalon homeobox 1;DMBX1;LCA7;OTX3 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | CRX |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human CRX Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes,including the opsin genes.Acts synergistically with other transcription factors,e.g.NRL and RX,to regulate photoreceptor cell-specific gene transcription.Essential for the maintenance of mammalian photoreceptors. |
实际分子量 | 37KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Cone-rod homeobox protein is a protein that in humans is encoded by the CRX gene.The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells.This homeodomain protein is necessary for the maintenance of normal cone and rod function.Mutations in this gene are associated with photoreceptor degeneration,Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2.Several alternatively spliced transcript variants of this gene have been described,but the full-length nature of some variants has not been determined. |
Uniprot ID | O43186 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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