加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

Caspase 3/CASP3抗体图片
产品货号:
Z32173
中文名称:
Caspase 3/CASP3抗体
英文名称:
Anti-Caspase 3/CASP3 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Caspase 3/CASP3 Antibody
指标别名Apopain;CASP 3;CASP3;Caspase 3;Caspase 3/p17;Caspase3;CPP 32;CPP32;CPP32B;Cysteine protease CPP32;Protein Yama;SCA 1;SREBP cleavage activity 1
克隆性Monoclonal
检验物种human,mouse
应用范围WB,IHC,ICC/IF
基因名称CASP3
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human pro Caspase 3
实际分子量35KD
成分500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
纯化方式Affinity-chromatography
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Caspase 3 is a caspase protein which interacts with Survivin,XIAP,CFLAR,Caspase 8,HCLS1,Deleted in Colorectal Cancer,TRAF3 and GroEL.This gene which is located on 4q35 encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family.Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits,large and small,that dimerize to form the active enzyme.It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein,which is associated with neuronal death in Alzheimer's disease.And the caspase-3 activation in heart failure sequentially cleaves SRF and generates a truncated SRF that appears to function as a dominant-negative transcription factor.Additionally,the caspase-3 influence on bone mineral density should be considered in any in vivo application of caspase-3 inhibitors to the treatment of human disease.In erythroid precursors undergoing terminal differentiation,Hsp70 prevents active CASP3 from cleaving GATA1 and inducing apoptosis.
Uniprot IDP42574
基因名全称Caspase-3
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:20~100ICC/IF
Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100

相关搜索:Caspase 3/CASP3抗体Caspase 3抗体CASP3单抗Anti-Caspase 3/CASP3 Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3