产品货号:
Z32117
中文名称:
CLEC9A Purified抗体
英文名称:
Anti-CLEC9A Purified Antibody (Clone#8F9)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CLEC9A Purified Antibody (Clone#8F9) |
指标别名 | CD370;CLEC9A;DNGR1;UNQ9341 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | FCM,ICC |
基因名称 | CLEC9A |
克隆号 | 8F9 |
抗体来源 | Mouse |
抗体类型 | IgG2a |
免疫原 | RBL-2H3 cells expressing human CLEC9A fused to an HA epitope.The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370/CLEC9A (DNGR1),a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes. |
计算分子量 | 27kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | CD370/CLEC9A,also known as DNGR1,is a type II transmembrane glycoprotein with extracellular C-type lectin domain and intracellular ITAM-containing domain.Its expression is restricted to BDCA3+ conventional dendritic cells and to a subset of CD14+ CD16- monocytes.CD370 serves as a receptor for ubiquitous preformed acid-labile protein associated ligands that are exposed when the cell membrane is damaged,such as on necrotic cells.Its triggering by these ligands mediates recruitment and activation of the tyrosine kinase Syk and leads to their cross-presentation to the immune system. |
Uniprot ID | Q6UXN8 |
基因名全称 | C-type lectin domain containing 9A |
蛋白名全称 | C-type lectin domain family 9 member A |
推荐稀释比 | Flow cytometry:1~4μg/mL |
相关搜索:CLEC9A Purified抗体,CLEC9A Purified单抗,Anti-CLEC9A Purified Antibody (Clone#8F9)