产品货号:
Z32096
中文名称:
CRK II抗体
英文名称:
Anti-CRK II Antibody (Clone#3G11C1)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CRK II Antibody (Clone#3G11C1) |
指标别名 | Adapter molecule crk;CRK;CRKII;p38;Proto oncogene c Crk |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,IF,FCM,ELISA |
基因名称 | CRK |
克隆号 | 3G11C1 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant fragment of human Crk II expressed in E.Coli. |
计算分子量 | 34KD |
成分 | Ascitic fluid containing 0.03% sodium azide. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | CRK,also known as p38 or CRKII,is a protein that in humans is encoded by the CRK gene.This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins.It is mapped to 17p13.3.The CRK protein participates in the Reelin signaling cascade downstream of DAB1.The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways,recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
Uniprot ID | P46108 |
基因名全称 | Adapter molecule crk |
蛋白名全称 | Adapter molecule crk |
推荐稀释比 | WB 1:500~1:2000 IHC 1:200~1:1000 IF 1:200~1:1000 FC 1:200~1:400 ELISA 1:10000 |
相关搜索:CRK II抗体,CRK II单抗,Anti-CRK II Antibody (Clone#3G11C1)