产品货号:
Z32066
中文名称:
Claudin 18/CLDN18抗体
英文名称:
Anti-Claudin 18/CLDN18 Antibody (Clone#6G1)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Claudin 18/CLDN18 Antibody (Clone#6G1) |
指标别名 | claudin 18;CLDN18;SFTA5;SFTPJ |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | IHC |
基因名称 | CLDN18 |
克隆号 | 6G1 |
抗体来源 | Mouse |
免疫原 | Synthesized peptide derived from human Claudin 18 |
计算分子量 | 28KD |
成分 | Liquid form in PBS containing 50% glycerol,0.5% BSA & 0.02% sodium azide. |
纯化方式 | Claudin 18 (6G1) antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Claudin-18 is a protein that in humans is encoded by the CLDN18 gene.This gene encodes a member of the claudin family.Claudins are integral membrane proteins and components of tight junction strands.Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity and signal transductions.This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas.PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells.Alternatively spliced transcript variants encoding different isoforms have been identified. |
Uniprot ID | P56856 |
基因名全称 | Claudin-18 |
蛋白名全称 | Claudin-18 |
推荐稀释比 | IHC 1:500 |
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