产品货号：
Z31956
中文名称：
ECT2抗体
英文名称：
Anti-ECT2 Antibody (Clone#1691CT516.3.3)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ECT2 Antibody (Clone#1691CT516.3.3) |
| 指标别名 | Protein ECT2;Epithelial cell-transforming sequence 2 oncogene;ECT2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | ECT2 |
| 克隆号 | 1691CT516.3.3 |
| 抗体来源 | Mouse |
| 免疫原 | This ECT2 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 200-460 amino acids from human ECT2. |
| 计算分子量 | 104kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Guanine nucleotide exchange factor (GEF) that catalyzes the exchange of GDP for GTP.Promotes guanine nucleotide exchange on the Rho family members of small GTPases,like RHOA,RHOC,RAC1 and CDC42.Required for signal transduction pathways involved in the regulation of cytokinesis.Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis.Regulates the translocation of RHOA from the central spindle to the equatorial region.Plays a role in the control of mitotic spindle assembly;regulates the activation of CDC42 in metaphase for the process of spindle fibers attachment to kinetochores before chromosome congression.Involved in the regulation of epithelial cell polarity;participates in the formation of epithelial tight junctions in a polarity complex PARD3-PARD6-protein kinase PRKCQ-dependent manner.Plays a role in the regulation of neurite outgrowth.Inhibits phenobarbital (PB)- induced NR1I3 nuclear translocation.Stimulates the activity of RAC1 through its association with the oncogenic PARD6A-PRKCI complex in cancer cells,thereby acting to coordinately drive tumor cell proliferation and invasion.Also stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. |
| Uniprot ID | Q9H8V3 |
相关搜索：ECT2抗体，ECT2单抗，Anti-ECT2 Antibody (Clone#1691CT516.3.3)