产品货号:
Z31902
中文名称:
CD35/CR1抗体
英文名称:
Anti-CD35/CR1 Antibody (Clone#25C32)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD35/CR1 Antibody (Clone#25C32) |
指标别名 | C3b/C4b receptor;C3BR;CD35;Complement receptor type 1;CR1;KN |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | CR1 |
克隆号 | 25C32 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human CD35 |
实际分子量 | 224~300KD |
成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene.This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1.The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes,leukocytes,glomerular podocytes,and splenic follicular dendritic cells.The Knops blood group system is a system of antigens located on this protein.The protein mediates cellular binding to particles and immune complexes that have activated complement.Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas,mesangiocapillary glomerulonephritis,systemic lupus erythematosus and sarcoidosis.Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting,conferring protection against severe malaria.Alternate allele-specific splice variants,encoding different isoforms,have been characterized.Additional allele specific isoforms,including a secreted form,have been described but have not been fully characterized. |
Uniprot ID | P17927 |
基因名全称 | Complement receptor type 1 |
推荐稀释比 | Western blot (WB) 1:500~2000 IHC 1:50~1:200 |
相关搜索:CD35/CR1抗体,CD35抗体,CR1单抗,Anti-CD35/CR1 Antibody (Clone#25C32)