产品货号:
Z31859
中文名称:
CD46抗体
英文名称:
Anti-CD46 Antibody (Clone#9E9)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD46 Antibody (Clone#9E9) |
指标别名 | CD46;MCP;Membrane cofactor protein;MIC10;TLX;TRA2.10 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,FCM |
基因名称 | CD46 |
克隆号 | 9E9 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human CD46 (366-392aa YRYLQRRKKKGTYLTDETHREVKFTSL). |
实际分子量 | 50~70KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | protein G purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene.The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system.And the encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I,which protects the host cell from damage by complement.In addition,the encoded protein can act as a receptor for the Edmonston strain of measles virus,human herpesvirus-6,and type IV pili of pathogenic Neisseria.Finally,the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome.Alternatively spliced transcript variants encoding different isoforms have been described. |
Uniprot ID | P15529 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
基因名全称 | CD46 molecule,complement regulatory protein |
蛋白名全称 | Membrane cofactor protein |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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