产品货号：
Z31801
中文名称：
Cytokeratin 8/KRT8抗体
英文名称：
Anti-Cytokeratin 8/KRT8 Antibody (Clone#3G9)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cytokeratin 8/KRT8 Antibody (Clone#3G9) |
| 指标别名 | CARD2;Cell and organelle markers;CK 8;CK8;CYK8;Cytokeratin 8;Cytoskeleton Marker;K2C8;K8;keratin 8;KO;KRT8;Type II keratin Kb8 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,IF,ICC/IF,FCM |
| 基因名称 | KRT8 |
| 克隆号 | 3G9 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human Cytokeratin 8 recombinant protein (Position:D107-K325).Human Cytokeratin 8 shares 95.4% and 94.5% amino acid (aa) sequence identity with mouse and rat Cytokeratin 8,respectively. |
| 实际分子量 | 54KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Keratin,type II cytoskeletal 8,also known as°Cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene.This gene is a member of the type II keratin family clustered on the long arm of chromosome 12.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells.This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation.Mutations in this gene cause cryptogenic cirrhosis.Alternatively spliced transcript variants have been found for this gene. |
| Uniprot ID | P05787 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Immunofluorescence (IF) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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