产品货号：
Z31758
中文名称：
DJ-1/PARK7抗体
英文名称：
Anti-DJ-1/PARK7 Antibody (Clone#4B10)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DJ-1/PARK7 Antibody (Clone#4B10) |
| 指标别名 | DJ 1;DJ1;DJ-1;Oncogene DJ1;PARK7;PARK7;DJ-1;Parkinson disease protein 7;Protein DJ 1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PARK7 |
| 克隆号 | 4B10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human PARK7 recombinant protein (Position:A2-D189).Human PARK7 shares 91% amino acid (aa) sequence identity with both mouse and rat PARK7. |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Parkinson disease (autosomal recessive,early onset) 7,also known as DJ1,is a protein which in humans is encoded by the PARK7 gene.PARK7 belongs to the peptidase C56 family of proteins.PARK7 is mapped to chromosome 1p36.It acts as a positive regulator of androgen receptor-dependent transcription.It is also involved in tumorigenesis and in maintaining mitochondrial homeostasis.This gene may also function as a redox-sensitive chaperone,as a sensor foroxidative stress,and it apparently protects neurons against oxidative stress and cell death.It has been found that PARK7 mutations that impair transcriptional coactivator function can render dopaminergic neurons vulnerable to apoptosis and may contribute to the pathogenesis of Parkinson disease. |
| Uniprot ID | Q99497 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | parkinson protein 7 |
| 蛋白名全称 | Protein deglycase DJ-1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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