产品货号：
Z31699
中文名称：
CD71/TFRC抗体
英文名称：
Anti-CD71/TFRC Antibody (Clone#MEM-75)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD71/TFRC Antibody (Clone#MEM-75) |
| 指标别名 | CD71;p90;sTfR;T9;TFR;TFR1;TFRC;TR;Transferrin receptor protein 1;TRFR |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,ICC |
| 基因名称 | TFRC |
| 克隆号 | MEM-75 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | NALM-6 human pre-B cell line.The antibody MEM-75 reacts with an extracellular epitope of CD71 antigen (transferrin receptor),a 95kDa type II homodimeric transmembrane glycoprotein expressed on activated B and T lymphocytes,macrophages and erythroid precursors;it is lost on resting blood leukocytes.The antibody MEM-75 does not block binding of transferrin to the receptor. |
| 计算分子量 | 85kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes.Upon binding of holotransferrin (complex of transferrin and iron ions),CD71 is internalized by clathrin-mediated endocytosis.Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions,whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface,where it is released upon exposure to normal pH.CD71 is also involved in uptake of non-transferrin bound iron. |
| Uniprot ID | P02786 |
| 基因名全称 | Transferrin receptor |
| 蛋白名全称 | Transferrin receptor protein 1 |
| 推荐稀释比 | Flow cytometry:4μg/mL. |
相关搜索：CD71/TFRC抗体，CD71抗体，TFRC单抗，Anti-CD71/TFRC Antibody (Clone#MEM-75)