产品货号:
Z31517
中文名称:
DDR1抗体
英文名称:
Anti-DDR1 Antibody (Clone#1464CT339.1.54)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DDR1 Antibody (Clone#1464CT339.1.54) |
指标别名 | CAK;CD167;Cell adhesion kinase;DDR;DDR1;EDDR1;HGK2;Mammary carcinoma kinase 10;MCK 10;MCK10;NEP;NTRK4;Protein tyrosine kinase 3A;Protein tyrosine kinase RTK 6;PTK3;PTK3A;RTK6;TRK E;TRKE;Tyrosine kinase DDR;Tyrosine protein kinase CAK |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | DDR1 |
克隆号 | 1464CT339.1.54 |
抗体来源 | Mouse |
免疫原 | This DDR1 antibody is generated from a mouse immunized with a recombinant protein. |
计算分子量 | 101kDa |
成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix,remodeling of the extracellular matrix,cell migration,differentiation,survival and cell proliferation.Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases.Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2,MMP7 and MMP9,and thereby facilitates cell migration and wound healing.Required for normal blastocyst implantation during pregnancy,for normal mammary gland differentiation and normal lactation.Required for normal ear morphology and normal hearing (By similarity).Promotes smooth muscle cell migration,and thereby contributes to arterial wound healing.Also plays a role in tumor cell invasion.Phosphorylates PTPN11. |
Uniprot ID | Q08345 |
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