产品货号:
Z31353
中文名称:
CXCL4/PF4抗体
英文名称:
Anti-CXCL4/PF4 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-CXCL4/PF4 Antibody |
| 指标别名 | C X C motif chemokine 4;CXCL4;Iroplact;Oncostatin A;PF 4;PF4;platelet factor 4;SCYB4 |
| 克隆性 | Monoclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC,IP |
| 基因名称 | PF4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human PF4 Released during platelet aggregation.Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.Chemotactic for neutrophils and monocytes.Inhibits endothelial cell proliferation,the short form is a more potent inhibitor than the longer form. |
| 实际分子量 | 11~26KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4).By in situ hybridization,the CXCL4 gene is mapped to chromosome 4q12-q21.Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels,thereby inhibiting local antithrombin III activity and promoting coagulation.As a strong chemoattractant for neutrophils and fibroblasts,PF4 probably has a role in inflammation and wound repair. |
| Uniprot ID | P02776 |
| 推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 |
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