产品货号:
Z31290
中文名称:
DFF45/DFFA抗体
英文名称:
Anti-DFF45/DFFA Antibody (Clone#OTI5C4)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DFF45/DFFA Antibody (Clone#OTI5C4) |
指标别名 | DFF 45;DFF1;DFF45;DFF45/DFFA;DFFA;ICAD;Inhibitor of CAD |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IF |
基因名称 | DFFA |
克隆号 | OTI5C4 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human DFFA (NP_004392) produced in E.coli. |
实际分子量 | 36.3KD |
成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 0.2mg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development.The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units.DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits.DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis.DFF becomes activated when DFFA is cleaved by caspase-3.The cleaved fragments of DFFA dissociate from DFFB,the active component of DFF.DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis.Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Uniprot ID | O00273 |
基因名全称 | DNA fragmentation factor subunit alpha|DNA fragmentation factor 45kDa subunit|DFF-45|Inhibitor of CAD|ICAD |
推荐稀释比 | Western blot (WB) 1:2500~5000 Immunofluorescence (IF) 1:50~100 |
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