产品货号：
Z31258
中文名称：
eNOS/NOS3抗体
英文名称：
Anti-eNOS/NOS3 Antibody (Clone#6H2)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-eNOS/NOS3 Antibody (Clone#6H2) |
| 指标别名 | cNOS;Constitutive NOS;EC NOS;ECNOS;Endothelial NOS;eNOS;NOS type III;NOS3;NOSIII |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | IHC,ELISA |
| 基因名称 | NOS3 |
| 克隆号 | 6H2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Purified recombinant fragment of human NOS3 expressed in E.Coli. |
| 计算分子量 | 133KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | NOS3(Nitric Oxide Synthase 3),also called ENOS,a?nitric oxide synthase?that generates?NO?in?blood vessels?and is involved with regulating?vascular tone?by inhibiting?smooth muscle?contraction and platelet?aggregation.The NOS3 gene is mapped on 7q36.1.Variations in this gene are associated with susceptibility to?coronary spasm.?Fulton et al.?(1999) concluded the eNOS is an AKT substrate linking signal transduction by AKT to the release of the gaseous second messenger nitric oxide.?AKT mediates the activation of eNOS,leading to increased nitric oxide production.Inhibition of the PI3K AKT pathway or mutation of the AKT site on eNOS protein at serine-1177 attenuated the serine phosphorylation and prevented the activation of eNOS.RT-PCR analysis showed that expression of?NOS3?in human umbilical vein endothelial cells (HUVECs) and human aortic vascular smooth muscle cells (HAOVSMCs) was inversely proportional to that of NOS3AS. |
| Uniprot ID | P29474 |
| 基因名全称 | Nitric oxide synthase,endothelial |
| 蛋白名全称 | Nitric oxide synthase,endothelial |
| 推荐稀释比 | IHC 1:200～1:1000 ELISA 1:10000 |
相关搜索：eNOS/NOS3抗体，eNOS抗体，NOS3单抗，Anti-eNOS/NOS3 Antibody (Clone#6H2)