产品货号:
Z31203
中文名称:
E-cadherin/CDH1抗体
英文名称:
Anti-E-cadherin/CDH1 Antibody (Clone#9G2)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-E-cadherin/CDH1 Antibody (Clone#9G2) |
指标别名 | Arc 1;Cadherin 1;CD324;CDH1;CDHE;E cadherin;ECAD;E-cad;E-cadherin;LCAM;UVO;Uvomorulin |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,IF,ICC/IF,FCM |
基因名称 | CDH1 |
克隆号 | 9G2 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | E.coli-derived human E Cadherin recombinant protein (Position:A286-A703).Human E Cadherin shares 79.7% and 80.9% amino acid (aa) sequence identity with mouse and rat E Cadherin,respectively. |
实际分子量 | 130KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | protein G purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | CDH1 (Cadherin 1),also known as ECAD or UVO,is a protein that in humans is encoded by the CDH1 gene.Cadherin-1 is a classical member of the cadherin superfamily.By Southern analysis of DNA from a panel of mouse-human somatic cell hybrids,Mansouri et al.(1987,1988) assigned the UVO gene to 16q (16p11-qter).Frebourg et al.(2006) found that in human embryos CDH1 is highly expressed at 4 and 5 weeks in the frontonasal prominence and at 6 weeks in the lateral and medial nasal prominences,and is therefore expressed during critical stages of lip and palate development.CDH1 is involved in mechanisms regulating cell-cell adhesions,mobility and proliferation of epithelial cells.Has a potent invasive suppressor role.It is a ligand for integrin alpha-E/beta-7. |
Uniprot ID | P12830 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunocytochemistry in fixed cells 1:50~400 Immunofluorescence (IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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