产品货号:
Z31156
中文名称:
DR5/TNFRSF10B抗体
英文名称:
Anti-DR5/TNFRSF10B Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DR5/TNFRSF10B Antibody |
指标别名 | CD262;Death receptor 5;DR5;KILLER;KILLER/DR5;TNFRSF10B;TRAIL R2;TRAIL receptor 2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IP,FCM |
基因名称 | TNFRSF10B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human DR5 |
实际分子量 | 48KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | TNFRSF10B(Tumor necrosis factor receptor superfamily,member 10b) is a human gene.It is also known as DR5,CD262,KILLER,TRICK2,TRICKB,ZTNFR9,TRAILR2,TRICK2A,TRICK2B,TRAIL-R2,KILLER/DR5.The protein encoded by this gene is a member of the TNF-receptor superfamily,and contains an intracellular death domain.This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand(TNFSF10/TRAIL/APO-2L),and transduces apoptosis signal.Mice have a homologous gene,tnfrsf10b,that has been essential in the elucidation of the function of this gene in humans.Studies with FADD-deficient mice suggested that FADD,a death domain containing adaptor protein,is required for the apoptosis mediated by this protein.By analysis of radiation hybrid panels,Walczak et al.(1997) mapped the TRAILR2 gene to chromosome 8p22-p21.Northern blot analysis indicated that TRAILR2 was expressed as a 4.4-kb mRNA in all tissues tested,with the highest levels of expression in peripheral blood lymphocytes,spleen,and ovary. |
Uniprot ID | O14763 |
基因名全称 | Tumor necrosis factor receptor superfamily member 10B |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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