
产品货号:
Z31155
中文名称:
DROSHA抗体
英文名称:
Anti-DROSHA Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DROSHA Antibody |
指标别名 | DROSHA;ETOHI2;HSA242976;p241;RANSE3L;Ribonuclease 3;Ribonuclease III;ribonuclease type III;nuclear;RN3;RNase III;RNASE3L;RNASEN |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ICC/IF,FCM |
基因名称 | DROSHA |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Drosha |
实际分子量 | 159KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene.This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex,which catalyzes the initial processing step of microRNA (miRNA) synthesis.The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus,yielding the precursor miRNA (pre-miRNA),which is then exported to the cytoplasm for further processing.In a human cell line lacking a functional copy of this gene,canonical miRNA synthesis is reduced.Somatic mutations in this gene have been observed in human patients with kidney cancer. |
Uniprot ID | Q9NRR4 |
基因名全称 | Ribonuclease 3 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 Flow cytometry (FCM) 1:20 |
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