产品货号：
Z31107
中文名称：
ERCC1抗体
英文名称：
Anti-ERCC1 Antibody (Clone#OTI1A3)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ERCC1 Antibody (Clone#OTI1A3) |
| 指标别名 | COFS4;ERCC1;UV20 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,IF,FCM |
| 基因名称 | ERCC1 |
| 克隆号 | OTI1A3 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Full-length protein expressed in 293T cell transfected with human ERCC1 expression vector |
| 实际分子量 | 32.6KD |
| 成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | The product of this gene functions in the nucleotide excision repair pathway,and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin.The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4),and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion.The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks.Mutations in this gene result in cerebrooculofacioskeletal syndrome,and polymorphisms that alter expression of this gene may play a role in carcinogenesis.Multiple transcript variants encoding different isoforms have been found for this gene.The last exon of this gene overlaps with the CD3e molecule,epsilon associated protein gene on the opposite strand. |
| Uniprot ID | P07992 |
| 基因名全称 | ERCC excision repair 1,endonuclease non-catalytic subunit |
| 蛋白名全称 | DNA excision repair protein ERCC-1 |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:50 Immunofluorescence (IF) 1:100 Flow cytometry (FCM) 1:100 |
相关搜索：ERCC1抗体，ERCC1单抗，Anti-ERCC1 Antibody (Clone#OTI1A3)