产品货号:
Z31094
中文名称:
ERGIC-53/LMAN1抗体
英文名称:
Anti-ERGIC-53/LMAN1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ERGIC-53/LMAN1 Antibody |
指标别名 | ERGIC 53;ERGIC-53;F5F8D;FMFD1;gp58;Lectin mannose binding 1;lectin;mannose binding;1;LMAN1;MCFD1;MR60;Protein ERGIC 53 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | LMAN1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human LMAN1 Mannose-specific lectin.May recognize sugar residues of glycoproteins,glycolipids,or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins,lipids,or both.The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. |
实际分子量 | 58KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Protein ERGIC-53 also known as ER-Golgi intermediate compartment 53kDa protein or lectin mannose-binding 1 is a protein that in humans is encoded by the LMAN1 gene.It is mapped to 18q21.32.The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum,endoplasmic reticulum-Golgi intermediate compartment,and cis-Golgi,functioning as a cargo receptor for glycoprotein transport.The protein has an N-terminal signal sequence,a calcium-dependent and pH-sensitive carbohydrate recognition domain,a stalk region that functions in oligomerization,a transmembrane domain,and a short cytoplasmic domain required for organelle targeting.Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. |
Uniprot ID | P49257 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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